Wednesday, August 6, 2014

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What is Polymyalgia Rheumatica? Polymyalgia Rheumatica (PMR) is a disease that affects people over age 50, women are afetas more often than men, typically causing stiffness and pain in neck, shoulders and hips for at least four weeks. Muscle pain can manifest associated with fatigue, weight loss, low grade fever and depression.
What is Giant cell arteritis (GCA)? ACG is characterized by an inflammatory process directed against the arterial vessel pink eye symptoms wall, extra-cranial head, originating from the subclavian artery. Due to the high frequency of involvement pink eye symptoms of the temporal arteries (lateral head), this disease is also known as temporal arteritis. The inflammation of the vessel walls leads to narrowing of the blood flow, causing symptoms of vascular insufficiency in the surrounding tissues. The ACG occurs almost exclusively in people over the age of 50 years, and the incidence increases progressively with age, and women are more affected. The most common symptom is headache, usually in the region pink eye symptoms of the temples. Also chewing pain along the temporo-mandibular joints. When there is involvement of ocular arteries blurred vision, diplopia pink eye symptoms (double vision) and / or blindness in one or both eyes suddenly can occur. Symptoms of general impairment caused pink eye symptoms by systemic pink eye symptoms inflammation, such as fatigue, loss of appetite, weight loss, low-grade fever may accompany or precede the more specific frame. The two diseases appear pink eye symptoms to be linked, since about 10 to 15% of patients with PMR also have GCA, and the reverse occurs in nearly 40% of patients.
PMR is a syndrome diagnosis for which there are no specific laboratory tests. The diagnosis pink eye symptoms is suggestive evidence when there are clinical history and physical examination, associated with abnormal laboratory test results consistent with inflammatory activity, measured by the erythrocyte pink eye symptoms sedimentation rate (ESR) and C-reactive protein (CRP) quite high. The final diagnosis of GCA is made by biopsy of the temporal artery. However, palpation of the artery with nodules on its surface, or a difference of temporal pulse strongly suggests the diagnosis. The evaluation dopplerfluxometric or by local ultrasound may be useful.
Treatment The goal of treatment pink eye symptoms of PMR and GCA is to relieve symptoms, and in the case of ACG prevent further tissue damage, particularly to blindness. The recommended and most widely used drug is the corticosteroid under strict medical supervision. Treatment usually extends pink eye symptoms for two years or more. In some cases resistant, immunosuppressants may be employed. Whatever the treatment used must be remembered the high risk for side effects, since we are dealing pink eye symptoms with elderly patients.
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